Toxic Multinodular Goiter

Toxic multinodular goiter (TMNG), also known as multinodular toxic goiter (MNTG), is an active multinodular

goiter

 associated with

hyperthyroidism

. It is a common cause of hyperthyroidism. In which there is excess production of thyroid hormones from functionally autonomous thyroid nodules, which do not require stimulation from thyroid-stimulating hormone (TSH).
It is the second most common cause of hyperthyroidism (after Graves' disease) in the developed world, whereas iodine deficiency is the most common cause of hypothyroidism in developing-world countries where the population is iodine-deficient.
Symptoms

Mass or swelling at the neck

  • At the center

  • Irregular surface

  • Immobile mass

  • Painless

common

Depression

or Feeling moody

common

Poor appetite

or Excessive appetite

common

Increased sensitivity to heat

common

Irregular heartbeat

common

Weight loss

common

Rapid heart rate

common

Thinning or loss of hair anywhere

common

Excessive sweating

Shaking

  • Resting

  • Both sides

Sudden hot sensation

Bulging eyeballs

Irregular periods

Difficulty breathing

Noise while breathing

or Swallowing difficulties

  • Foods and drinks

Difficulty passing stool

  • Chronic

Strained voice

Fatigue

Risk factors

Iodine deficiency

Radiation therapy

  • Neck

Family history of thyroid cancer

Treatment
1-Radioiodine therapy. One treatment for both toxic and non-toxic goiters is radioiodine therapy. 2-Thyroid medication. If the goiter and its nodules are relatively small in size, a doctor may recommend taking a thyroid hormone medication, such as levothyroxine (Synthroid). 3-Thyroidectomy: typically involves removal of the entire thyroid, especially if nodules are present on both sides of the thyroid or the thyroid is enlarged and causing pressure in the neck or difficulty with swallowing.
Recommended specialist

If you have Toxic Multinodular Goiter, then a visit to an endocrinologist is highly recommended.

Contact an

Endocrinologist

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