Primary Sclerosing Cholangitis

Primary Sclerosing Cholangitis is a long-term progressive disease of the liver and

gallbladder

characterized by inflammation and scarring of the bile ducts, which normally allow bile to drain from the gallbladder, meaning that bile ducts carry the digestive liquid "bile" from your liver to your small intestine.
An immune system reaction to an infection or toxin may trigger the disease in people who are genetically predisposed to it.
Symptoms

Itchy skin

  • At palms, At soles

  • At scalp, At chest, At lower extremity, At genital, At neck, Buttocks, At face, At back, At nose, Between the toes, At upper extremity, Around the anus, At feet, At abdomen, At breast(s)

  • Occurs or worsens at night

common

Fatigue

common

Yellow eyes or skin

or Dark urine

or Poop with light color

Abdominal pain

  • In the upper right region

Weight loss

Fever

  • Less than 38°C (100.4°F), Greater than or equal to 38°C (100.4°F)

Fat in stool

Swollen blood vessels on the skin that looks like a spiders web

  • Over upper body

or Skin rash and redness

  • At hands

or Loss of muscle mass

or Swollen belly

Risk factors

Inflammation of the colon

Treatment
Treatments for primary sclerosing cholangitis focus on managing complications and monitoring liver damage. Many medications have been studied in people with primary sclerosing cholangitis, but so far none have been found to slow or reverse the liver damage associated with this disease. No effective medical treatment for primary sclerosing cholangitis is known. Its most definitive treatment is a liver transplant, but it can recur after transplantation
Recommended specialist

If you have Primary Sclerosing Cholangitis, then a visit to a gastroenterologist is highly recommended.

Contact a

Gastroenterologist

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