Erythema Nodosum

Treatment varies for each person diagnosed with erythema nodosum and depends on what caused your symptoms. In most patients, erythema nodosum is a self-limited disease and requires only symptomatic relief using nonsteroidal anti-inflammatory drugs (NSAIDs), cool wet compresses, elevation, and bed rest. Treatment could include: Managing or treating any underlying conditions or infections. Stop taking medicine that caused your symptoms. Don’t stop taking a medication unless your provider tells you it’s safe to do so. Taking medicine to reduce symptoms. Elevating the affected part of your body, like placing your leg on a pillow when lying down. Resting and avoiding strenuous activity. Erythema nodosum can resolve on its own after a few weeks to months and doesn’t always need treatment.