Cronkhite Canada Syndrome

Cronkhite–Canada syndrome (CCS) is a rare syndrome characterized by multiple

polyps

of the

digestive tract

. There is no specific test to diagnose Cronkhite–Canada syndrome. Diagnosis is based on symptoms and features of the disease.
The typical onset of Cronkhite-Canada syndrome is during middle or old age. The average age is 59 years; the range is 31-86 years. Some reports suggest that the disease may remain asymptomatic, thus not being diagnosed for a long time. Most patients are older than 50 years at the time of presentation.
Symptoms

Nail discoloration

  • Yellow, Brown, White color on nails

or Small depressions on the nails

or Nails break easily

or Painless detachment of the nail from the nail bed

or Splitting of the fingernails

common

Darkening of skin on the hands, arms, neck and face

common

Diarrhea

  • For 2 weeks or more

  • Large quantity

  • Watery

common

Thinning or loss of hair anywhere

  • Bald spots

common

Weight loss

common

Fatigue

common

Poor appetite

common

Abdominal pain

  • In the upper right region, In the bottom right region, In the upper left region, Lower, In the bottom left region, Nonspecific, non-focal, Located in middle upper region

common

Black stool

Rapid heart rate

Feel like vomiting

or Throwing up

Impaired taste

Fainting

or Dizziness

Anemia

Tongue inflammation

Treatment
Bacterial overgrowth in the intestines, which can cause malabsorption, may be treated with antibiotics. In rare cases, symptoms have resolved for no apparent reason (spontaneous remission). Surgical removal of polyps may help to relieve some of the symptoms of Cronkhite-Canada syndrome.
Recommended specialist

If you have Cronkhite Canada Syndrome, then a visit to a gastroenterologist is highly recommended.

Contact a

Gastroenterologist

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