Treatments include: 1-Antibiotics: Taking antibiotics is the most commonly prescribed treatment for prostatitis. 2-Alpha-blockers: These medications help relax the bladder neck and the muscle fibers where your prostate joins your bladder. 3-Anti-inflammatory agents: Nonsteroidal anti-inflammatory drugs (NSAIDs) might make you more comfortable. 4-Limit or avoid alcohol, caffeine, and spicy or acidic foods, which can irritate your bladder. Avoid activities that can irritate your prostate, such as prolonged sitting or bicycling. Drink plenty of caffeine-free beverages. This will cause you to urinate more and help flush bacteria from your bladder.