Acute Interstitial Nephritis

Acute interstitial nephritis (AIN) is a sudden condition characterized by the

inflammation

 of the

kidneys

. The main functions of your kidneys are to filter your blood and to get rid of waste from your body. The kidney tubules reabsorb water and important organic substances from the filtered blood and secrete substances you don’t need into your urine for removal from your body. Swelling of these tubules can cause a number of kidney symptoms that range from mild to severe.
Acute interstitial nephritis may be more severe and more likely to lead to long-term or permanent kidney damage in older people.
Symptoms

Decreased urine

common

Joint pain

common

Fever

  • Greater than or equal to 38°C (100.4°F), Less than 38°C (100.4°F)

Blood in urine

or Dark urine

Skin rash and redness

Abdominal pain

  • Flank pain

Pain discomfort or burning when urinating

Fatigue

or Feel like vomiting

or Throwing up

Risk factors

Use of Proton-Pump Inhibitors

or Use of penicillin

or Use of cephalosporin

or Use of trimethoprim sulfamethoxazole

or Use of sulfonamide

or Use of diuretics

or Rifampin antibiotic

or Use of Nonsteroidal Anti-Inflammatory Drug

Infection in any part of urinary system

or Poor genital hygiene

Systemic Lupus Erythematosus (SLE)

or Sarcoidosis

Uncircumcised penis

Recent upper respiratory tract infection

Treatment
When AIN is caused by a drug allergy, the only treatment needed may be drug removal. Other cases of AIN can be treated with anti-inflammatory medications. Quick treatment often leads to a full recovery.
Recommended specialist

If you have Acute Interstitial Nephritis, then visit a general internist as soon as possible.

Contact a

General internist

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