Ovarian Insufficiency

Primary Ovarian Insufficiency

Primary ovarian insufficiency (POI) occurs when the ovaries stop functioning as they should before age 40. When this happens, your ovaries don't produce typical amounts of the hormone estrogen or release eggs regularly. This condition is also called premature ovarian failure and often leads to infertility. Ovarian insufficiency is considered primary if the ovary fails to function normally in response to appropriate gonadotropin stimulation provided by the hypothalamus and pituitary.

At this time, there is no way to prevent primary ovarian insufficiency. But you can take steps to protect your overall health. Women with this condition have a higher risk of bone thinning and fractures (osteoporosis), diabetes, and heart disease.
  • Symptoms
  • Absence of period

    • Absence of period

    or Irregular periods


    Inability to conceive a child


    Sudden hot sensation

    Excessively dry vagina

    or Pain during sexual intercourse

    Easily get bone fractures

    Low blood pressure

    or Skin hyperpigmentation

  • Risk factors
  • Treatment
  • Currently, there is no proven treatment to restore normal function to a woman's ovaries. But there are treatments for some of the symptoms of POI. There are also ways to lower your health risks and treat the conditions that POI can cause: 1-Hormone replacement therapy (HRT). HRT is the most common treatment. It gives your body the estrogen and other hormones that your ovaries are not making. HRT improves sexual health and decreases the risks for heart disease and osteoporosis. You usually take it until about age 50; that's about the age when menopause usually begins. 2-Calcium and vitamin D supplements. Because women with POI are at higher risk for osteoporosis, they should take calcium and vitamin D every day. 3-In vitro fertilization (IVF). If you have POI and you wish to become pregnant, you may consider trying IVF. 4-Regular physical activity and healthy body weight. Getting regular exercise and controlling your weight can lower your risk for osteoporosis and heart disease. 5-Treatments for associated conditions. If you have a condition that is related to POI, it is important to treat that as well. Treatments may involve medicines and hormones.
  • Recommended specialist
  • If you have Ovarian Insufficiency, then a visit to an obstetrician-gynecologist is recommended.

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