Primary Ovarian Insufficiency

Primary ovarian insufficiency (POI) occurs when the ovaries stop functioning as they should before age 40. When this happens, your ovaries don't produce typical amounts of the hormone estrogen or release eggs regularly. This condition is also called premature ovarian failure and often leads to infertility. Ovarian insufficiency is considered primary if the ovary fails to function normally in response to appropriate gonadotropin stimulation provided by the hypothalamus and pituitary.

Vaginal dryness

Amenorrhea

Irregular menstruation

Hypotensive

Diffuse skin hyperpigmentation

Weak bones that break or fracture easily

Infertility

Hot flashes

Dyspareunia

Ovarian Insufficiency