Primary ciliary dyskinesia

Primary ciliary dyskinesia is a rare genetic disease affecting cilia. When cilia are not appropriately functional, mucus and bacteria accumulate causing infections and clogging of the lungs, ears, and sinuses. Patients with primary ciliary dyskinesia might also have their internal organs on the opposite side of normal. This disease usually presents since birth with recurrent lung and sinus infections but it has varying degrees of severity. It can also affect the fluid around the brain and cause hydrocephalus. In adulthood, it can affect fertility by making sperms and eggs unable to move properly, which affects fertilization and causes ectopic pregnancies.