Fatigue

Swelling or lump in eyelid

or Enlarged feet or ankle

or Swelling in lower leg

• In both lower legs

or Urine with bubbles unrelated to speed of urination or bladder fullness

Abdominal mass

• Right upper quadrant

• Located in middle upper region

Swollen neck vein

or Difficulty breathing

• Occurs or worsens with exertion

• During sleep, Occurs when lying flat

Poor appetite

Unexplained skin injury

or Bleeding easily or difficulty controlling bleeding

Weight loss

Waxy skin

Throwing up

• Blood in vomit, Dark brown liquid

or Black stool

or Bleeding from anus

Irregular heartbeat

or Fainting

or Dizziness

Muscle pain

Swollen belly

Tongue with wavy edges

or Enlarged tongue without inflammation or swelling

Fat in stool

A burning feeling in thigh

or A burning feeling in arms

or Gradual lower limb weakness

or Numbness or tingling in shoulders arms or hands

or A burning feeling in legs or feet

or Numbness or tingling in legs, feet, or buttocks

or Gradual upper limb weakness

Feel like vomiting

or Abdominal bloating

or Abdominal pain

• Nonspecific, non-focal

Numbness or tingling in hand

• Palmar aspect

• Radiates to fingers

• Occurs or worsens with activities that involve sustained flexing or extending the wrist

• Occurs or worsens at night

or Pain in arms

or Weakness of hand

Decreased urine

Alternation between diarrhea and constipation

Noise while breathing

or Swallowing difficulties

or Strained voice

Jaw pain

Enlarged shoulder

• Both shoulders

Dry eyes

or Blurred vision

or Difficulty hearing

• Both ears

Multiple myeloma

or Inflammation of the colon

• Crohns disease

or Rheumatoid arthritis

Family history of amyloidosis

History of alzheimer disease

Kidney failure or on dialysis