Primary Sclerosing Cholangitis

Primary Sclerosing Cholangitis is a long-term progressive disease of the liver and gallbladder characterized by inflammation and scarring of the bile ducts, which normally allow bile to drain from the gallbladder, meaning that bile ducts carry the digestive liquid "bile" from your liver to your small intestine.

An immune system reaction to an infection or toxin may trigger the disease in people who are genetically predisposed to it.
  • Symptoms
  • Itchy skin

    • Occurs or worsens at night

    • At palms and soles




    Yellow eyes or skin

    or Dark urine

    or Poop with light color

    Abdominal discomfort other than pain

    or Abdominal pain

    • In the upper right region

    Weight loss


    • Less than 38°C (100. 4°F), Greater than or equal to 38°C (100.4°F)

    Fat in stool

    Swollen blood vessels on the skin that looks like a spiders web

    • Over upper body

    or Skin rash and redness

    • At hands

    or Loss of muscle mass

    or Swollen belly

  • Risk factors
  • Inflammation of the colon

  • Treatment
  • Treatments for primary sclerosing cholangitis focus on managing complications and monitoring liver damage. Many medications have been studied in people with primary sclerosing cholangitis, but so far none have been found to slow or reverse the liver damage associated with this disease. No effective medical treatment for primary sclerosing cholangitis is known. Its most definitive treatment is a liver transplant, but it can recur after transplantation
  • Recommended specialist
  • If you have Primary Sclerosing Cholangitis, then a visit to a gastroenterologist is highly recommended.

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